| 01 |  Fernando Gaviria | 1994 |  UAE Team Emirates | 04:08:03 |
| 02 |  Rudy Barbier | 1992 |  Israel Start-Up Nation | + 00 |
| 03 | Alvaro Hodeg | 1996 |  Deceuninck – Quick Step | + 00 |
| 04 |  Peter Sagan | 1990 |  Bora – Hansgrohe | + 00 |
| 05 | Piet Allegaert | 1995 | Cofidis | + 00 |
| 06 | Bert Van Lerberghe | 1992 | Deceuninck – Quick Step | + 00 |
GENERAL TRAS 4ª ETAPA
| 01 | Remco Evenepoel | 2000 | Deceuninck – Quick Step | 11:42:38 |
| 02 |  Filippo Ganna | 1996 | Italy | + 33 |
| 03 |  Óscar Sevilla | 1976 | Team Medellin | + 01:09 |
| 04 |  Nelson Oliveira | 1989 | Movistar Team | + 01:26 |
| 05 |  Brandon McNulty | 1998 | UAE Team Emirates | + 01:27 |
| 06 |  Maciej Bodnar | 1985 | Bora – Hansgrohe | + 01:28 |
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